Researchers identify how inflammation spreads through the brain after injury and Findings could transform understanding of brain injury, disease
The concept of Traumatic Brain Injury being a “process” and not just an “event,” has been discussed by experts in recent years. A new study published in the Journal of Neuroinflammation may change our perception of neuro-degeneration.
This new understanding has the potential to transform how brain inflammation is understood, and, ultimately, how it is treated. The researchers showed that microparticles derived from brain inflammatory cells are markedly increased in both the brain and the blood following experimental traumatic brain injury (TBI). Research has found that neuroinflammation often goes on for years after TBI, causing chronic brain damage.
Chronic inflammation has been increasingly implicated in the progressive cell loss and neurological changes that occur after TBI. These inflammatory microparticles may be a key mechanism for chronic, progressive brain inflammation and may represent a new target for treating brain injury.